Disease: TARSAL-CARPAL COALITION SYNDROME
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC6 P12956 X-ray repair cross complementing 6 Enzyme 1.00 0.552 0.769
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
VIM P08670 vimentin 0.71 0.372 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
POU5F1P4 POU class 5 homeobox 1 pseudogene 4 0.452 0.808
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 0.452 0.808
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PMAIP1 Q13794 phorbol-12-myristate-13-acetate-induced protein 1 0.11 0.559 0.808
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MIR21 microRNA 21 0.363 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923